Archive for October, 2010

Scientists in India join hands to develop biofuel from microalgae

Posted On: October 31, 2010

Scientists from across the country of India belonging to a consortium of nine laboratories, are working on an ambitious project called ‘New Millennium India Technology Leadership Initiative’ ( NMITLI), to develop a viable and scalable process of biofuel from microalgae, undertaken by Council of Scientific and Industrial Research (CSIR), New Delhi.

The laboratories are Central Salt and Marine Chemicals Research Institute (CSMCRI), Bhavnagar, Department of Marine Living Resources, Andhra University (AU), Vishakapatnam, Calcutta University (CU), Kolkata, Indian Institute of Chemical Technology (IICT), Hyderabad, Indian Institute of Technology, Khargpur (IIT-KGP), National Chemical Laboratory (NCL), Pune, National Institute of Oceanography (NIO), Goa, National Institute of Ocean Technology (NIOT) and Chennai, National Institute of Interdisciplinary Science & Technology (NIIST), Thiruvananthapuram.

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Quebec City: Consortium BioMar-Innovation Holding Event: “Crossroads of the Sea: New marine extracts for the food industry and health”; November 9, 2010

Posted On: October 29, 2010

Background and objectives:

Increasingly present in products associated with health and well-being, ingredients and marine extracts have advantages over conventional sources of ingredients.

Program:

  • Market trends for products containing natural extracts of marine bioactive
  • Research currently underway at universities and research centers in Quebec and France
  • Examples of extracts and ingredients sold by Quebec companies

Exhibition of research projects related to marine biomass.

Organized in the framework of the Consortium BioMar-Innovation, an initiative of:

  • Centre québécois de valorisation and biotechnology
  • Center of Marine Biotechnology Research

In collaboration with:

Institute of Nutraceuticals and Functional Foods

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Research suggests that chitin is an effective alternative for adhesion barriers

Posted On: October 29, 2010

Comparison of the effects of an adhesion barrier and chitin on experimental epidural fibrosis.

Keskın FEsen H.

Karaman State Hospital, Department of Neurosurgery, Karaman, Turkey.

Abstract

Aim: Epidural fibrosis is an important factor for postoperative failed back syndrome development and causes clinical complaints in 6-25% of cases. An effective treatment modality has not been found yet. The aim of this study is to investigate the anti-adhesive effects of a novel agent chitin and compare these effects with a popular adhesion barrier collagen matrix. Material and Methods: 21 rabbits were allocated into three groups including 7 rabbits each. L5 total laminectomy was performed to all groups. No treatment was given to Group 1 (Control group). Collagen matrix was used in Group 2 and chitin was used in Group 3. Six weeks later all rabbits were sacrificed and the laminectomy areas were entirely resected and investigated histopathologically. Results: He and Revel grade III epidural fibrosis was detected in the control group. Statistically significant reduction of epidural fibrosis was achieved with both of the anti-adhesive agents, collagen matrix and chitin, when compared with the control group (p < 0.05). The results were not different between treatment groups (p > 0.05).

Conclusion: The novel agent chitin was found effective for preventing epidural fibrosis and this effect was not significantly different from the collagen matrix. In light of our findings we suggest that chitin is an effective alternative for adhesion barriers.

Turk Neurosurg. 2010 Oct;20(4):457-63. doi: 10.5137/1019-5149.JTN.3205-10.2.

Neptune Technologies & Bioressources Inc. moving into pharmaceutical market with launch of subsidiary Acasti Pharma Inc.’s Onemia

Posted On: October 29, 2010

Montreal’s Neptune Technologies & Bioressources Inc. said Monday it is moving into the pharmaceutical market with the launch of subsidiary Acasti Pharma Inc.’s Onemia at the Cardiometabolic Health Congress in Boston.

Onemia is a marine-based medical food, approced by regulators for the management of cardiometabolic disorders. It can be taken alone or in combination with prescribed heart drugs. It will be manufactured by Neptune and distributed through doctors initially under subcontract. Acasti is seeking partners to commercialize the product outside the United States.

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Marine Drugs, Volume 8, Issue 10 (October 2010), Pages 2546-2732 Released

Posted On: October 29, 2010

MDPI

The office of MDPI announce the publication of the following issue: Mar.
Drugs, Volume 8, Issue 10 (October 2010), Pages 2546-2732 at
http://www.mdpi.com/1660-3397/8/10/

Table of Contents:

Benjamin R. Gordon and William Leggat
Review: Symbiodinium—Invertebrate Symbioses and the Role
of Metabolomics
Mar. Drugs 2010, 8(10), 2546-2568; doi:10.3390/md8102546
http://www.mdpi.com/1660-3397/8/10/2546

Jean-Michel Kornprobst and Gilles Barnathan
Review: Demospongic Acids Revisited
Mar. Drugs 2010, 8(10), 2569-2577; doi:10.3390/md8102569
http://www.mdpi.com/1660-3397/8/10/2569

Andrey P. Tikunov, Christopher B. Johnson, Haakil Lee, Michael K. Stoskopf
and Jeffrey M. Macdonald
Article: Metabolomic Investigations of American Oysters Using 1H-NMR
Spectroscopy
Mar. Drugs 2010, 8(10), 2578-2596; doi:10.3390/md8102578
http://www.mdpi.com/1660-3397/8/10/2578

Vuyisile S. Thibane, Johan L. F. Kock, Ruan Ells, Pieter W. J. van Wyk and
Carolina H. Pohl
Article: Effect of Marine Polyunsaturated Fatty Acids on Biofilm Formation
of Candida albicans and Candida dubliniensis
Mar. Drugs 2010, 8(10), 2597-2604; doi:10.3390/md8102597
http://www.mdpi.com/1660-3397/8/10/2597

Jin-Shan Tang, Feng Zhao, Hao Gao, Yi Dai, Zhi-Hong Yao, Kui Hong, Jia Li,
Wen-Cai Ye and Xin-Sheng Yao
Article: Characterization and Online Detection of Surfactin Isomers Based
on HPLC-MSn Analyses and Their Inhibitory Effects on the Overproduction of
Nitric Oxide and the Release of TNF-α and IL-6 in LPS-Induced Macrophages
Mar. Drugs 2010, 8(10), 2605-2618; doi:10.3390/md8102605
http://www.mdpi.com/1660-3397/8/10/2605

Sunil Sagar, Mandeep Kaur and Kenneth P. Minneman
Review: Antiviral Lead Compounds from Marine Sponges
Mar. Drugs 2010, 8(10), 2619-2638; doi:10.3390/md8102619
http://www.mdpi.com/1660-3397/8/10/2619

Ping-Jyun Sung, Gung-Ying Li, Yin-Di Su, Mei-Ru Lin, Yu-Chia Chang,
Ting-Hsuan Kung, Chan-Shing Lin, Yung-Husan Chen, Jui-Hsin Su, Mei-Chin
Lu, Jimmy Kuo, Ching-Feng Weng and Tsong-Long Hwang
Article: Excavatoids O and P, New 12-Hydroxybriaranes from the Octocoral
Briareum excavatum
Mar. Drugs 2010, 8(10), 2639-2646; doi:10.3390/md8102639
http://www.mdpi.com/1660-3397/8/10/2639

Thomas Schmitt, Eva Keller, Sascha Dietrich, Patrick Wuchter, Anthony D.
Ho and Gerlinde Egerer
Article: Trabectedin for Metastatic Soft Tissue Sarcoma: A Retrospective
Single Center Analysis
Mar. Drugs 2010, 8(10), 2647-2658; doi:10.3390/md8102647
http://www.mdpi.com/1660-3397/8/10/2647

Linn Oftedal, Frode Selheim, Matti Wahlsten, Kaarina Sivonen, Stein Ove
Døskeland and Lars Herfindal
Article: Marine Benthic Cyanobacteria Contain Apoptosis-Inducing Activity
Synergizing with Daunorubicin to Kill Leukemia Cells, but not
Cardiomyocytes
Mar. Drugs 2010, 8(10), 2659-2672; doi:10.3390/md8102659
http://www.mdpi.com/1660-3397/8/10/2659

Ira Bhatnagar and Se-Kwon Kim
Review: Immense Essence of Excellence: Marine Microbial Bioactive
Compounds
Mar. Drugs 2010, 8(10), 2673-2701; doi:10.3390/md8102673
http://www.mdpi.com/1660-3397/8/10/2673

Ira Bhatnagar and Se-Kwon Kim
Review: Marine Antitumor Drugs: Status, Shortfalls and Strategies
Mar. Drugs 2010, 8(10), 2702-2720; doi:10.3390/md8102702
http://www.mdpi.com/1660-3397/8/10/2702

Isabel Nogueira, Alexandre Lobo-da-Cunha, António Afonso, Socorro Rivera,
Joana Azevedo, Rogério Monteiro, Rosa Cervantes, Ana Gago-Martinez and
Vítor Vasconcelos
Article: Toxic Effects of Domoic Acid in the Seabream Sparus aurata
Mar. Drugs 2010, 8(10), 2721-2732; doi:10.3390/md8102721
http://www.mdpi.com/1660-3397/8/10/2721

Algenol Biofuels Opens State-of-the-Art Labs in Lee County, Florida

Posted On: October 21, 2010

Algenol Biofuels Inc. celebrated the opening of its new state-of-the-art biofuels and green chemistry lab and R&D facility today in Fort Myers, Fla. The 40,000 square-foot facility houses an advanced algae biology, engineering, carbon dioxide (CO2) and green chemistry laboratory, as part of the larger Lee Integrated Biorefinery. The facility was made possible with a $10 million incentive grant from the Lee County Board of Commissioners.

The facility will house Algenol’s advanced biology and engineering laboratories and operations. An adjoining 4-acre outdoor R&D area and 36-acre outdoor commercialization area will hold the company’s proprietary photobioreactors—the containers that generate ethanol from algae, saltwater and CO2 using Algenol’s patented Direct to Ethanol™ technology. In addition to producing low-cost ethanol, Algenol is beginning to work on related projects, such as using its ethanol and other green chemicals as a replacement for petroleum in plastic and chemical building blocks. Furthermore, Algenol has formed a partnership with a local university, Florida Gulf Coast University, to assist in establishing programs for students interested in pursuing careers in the green chemistry and biofuels industries.

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Joint investigation by Aquapharm and Leatherhead seeks to uncover new natural preservatives from marine bacteria and fungi

Posted On: October 21, 2010

A new joint investigation by Aquapharm and Leatherhead is seeking to uncover new natural preservatives from marine bacteria and fungi.

Aquapharm Biodiscovery believes its substantial collection of marine bacteria and fungi from a variety of diverse sources could offer some solutions. It has teamed up with Leatherhead Food International to develop a source of naturally-derived anti-microbial compounds.

Based at the European Centre for Marine Biotechnology in Oban on Scotland’s West coast, Aquapharm uses it epigenetics platform to expose these microorganisms to stresses that they would not normally be exposed to, which allows conformational changes in the DNA structure and wakes up silent genetic pathways.

In this way the microorganisms can be stimulated to produce novel, biologically active compounds.

AquaPharm is drawn up its shortlist, Leatherhead Food Research – which has experience in the identification, evaluation and application of new preservatives for foods – will screen it against its collection of food spoilage organism to measure the preservative performance.

The results of the collaboration will be made available to industry via Leatherhead’s membership network and an industry partner or partners may further develop and commercialise them.

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Chitosan Offers Hope For Spinal Injury Patients

Posted On: October 17, 2010

Richard Borgens and his colleagues from the Center for Paralysis Research at the Purdue School of Veterinary Medicine have a strong record of inventing therapies for treating nerve damage. From Ampyra, which improves walking in multiple sclerosispatients to a spinal cord simulator for spinal injury victims, Borgens has had a hand in developing therapies that directly impact patients and their quality of life.

Another therapy that is currently undergoing testing is the use of polyethylene glycol (PEG) to seal and repair damaged spinal cord nerve cells. By repairing the damaged membranes of nerve cells, Borgens and his team can restore the spinal cord’s ability to transmit signals to the brain.

However, there is one possible clinical drawback: PEG’s breakdown products are potentially toxic. Is there a biodegradable non-toxic compound that is equally effective at targeting and repairing damaged nerve membranes? Borgens teamed up with physiologist Riyi Shi and chemist Youngnam Cho, who pointed out that some sugars are capable of targeting damaged membranes. Could they find a sugar that restored spinal cord activity as effectively as PEG? Borgens and his team publish their discovery that chitosan can repair damaged nerve cell membranes inThe Journal of Experimental Biology on 16 April 2010.

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Census of Marine Life Produces Huge Harvest

Posted On: October 16, 2010

First Census of Marine Life 2010: Highlights of a Decade of Discovery is now available.

A 64-page report that describes some of the scientific highlights of ten years of exploration, research and analysis undertaken by Census of Marine Life scientists. Included is a description of the Census research projects and organizational structure.

Great photos

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French omega-3 firm buys Canadian researcher

Posted On: October 16, 2010

French-based Polaris has purchased Canadian start-up Ocean Nutrasciences, for an undisclosed sum.

Polaris has been working in the nutritional lipid area for about 15 years and said the acquisition provided it with added innovation potential in marine ingredients for use in, nutraceutics, food and cosmetics”.

In particular, Ocean Nutrasciences has done a lot of work taking extracts from Northern shrimp which have been found to be high in astaxanthine, amino acids and omega-3 forms EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid).

In a statement Polaris said Ocean Nutrasciences, “develops, makes, values (via clinical studies) and markets marine ingredients (shellfish, algae and fish) exempt from organic solvents”.

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