Call for Papers: invitation to submit a research article, review article, short communication or a technical note in the field of Marine Biotechnology or related areas.

Submission Guidelines

Original and unpublished contributions that are not currently under review by another journal are solicited. All manuscripts must be prepared in English and should be submitted through the online submission system available at

http://www.ejbiotechnology.info/index.php/ejbiotechnology/about/submissions#onlineSubmissions

Table of Contents:

Jeen-Kuan Chen, Chao-Hsien Yeh, Lian-Chen Wang, Tzong-Horng Liou, Chia-Rui Shen and Chao-Lin Liu
Article: Chitosan, the Marine Functional Food, Is a Potent Adsorbent of Humic Acid
Mar. Drugs 2011, 9(12), 2488-2498; doi:10.3390/md9122488
http://www.mdpi.com/1660-3397/9/12/2488/

Oriol Sacristan-Soriano, Bernard Banaigs and Mikel A. Becerro
Article: Relevant Spatial Scales of Chemical Variation in Aplysina aerophoba
Mar. Drugs 2011, 9(12), 2499-2513; doi:10.3390/md9122499
http://www.mdpi.com/1660-3397/9/12/2499/

Jeannette Vera, Jorge Castro, Alberto Gonzalez and Alejandra Moenne
Review: Seaweed Polysaccharides and Derived Oligosaccharides Stimulate Defense Responses and Protection Against Pathogens in Plants
Mar. Drugs 2011, 9(12), 2514-2525; doi:10.3390/md9122514
http://www.mdpi.com/1660-3397/9/12/2514/

Nai-Lun Lee and Jui-Hsin Su
Article: Tetrahydrofuran Cembranoids from the Cultured Soft Coral Lobophytum crassum
Mar. Drugs 2011, 9(12), 2526-2536; doi:10.3390/md9122526
http://www.mdpi.com/1660-3397/9/12/2526/

Maria Mansson, Anita Nielsen, Louise Kjærulff, Charlotte H. Gotfredsen, Matthias Wietz, Hanne Ingmer, Lone Gram and Thomas O. Larsen
Article: Inhibition of Virulence Gene Expression in Staphylococcus aureus by Novel Depsipeptides from a Marine Photobacterium
Mar. Drugs 2011, 9(12), 2537-2552; doi:10.3390/md9122537
http://www.mdpi.com/1660-3397/9/12/2537/

Julianne Dyble, Duane Gossiaux, Peter Landrum, Donna R. Kashian and Steven Pothoven
Article: A Kinetic Study of Accumulation and Elimination of Microcystin-LR in Yellow Perch (Perca Flavescens) Tissue and Implications for Human Fish Consumption
Mar. Drugs 2011, 9(12), 2553-2571; doi:10.3390/md9122553
http://www.mdpi.com/1660-3397/9/12/2553/

Massimiliano Borgogna, Barbara Bellich and Attilio Cesàro
Review: Marine Polysaccharides in Microencapsulation and Application to Aquaculture: “From Sea to Sea”
Mar. Drugs 2011, 9(12), 2572-2604; doi:10.3390/md9122572
http://www.mdpi.com/1660-3397/9/12/2572/

Marcel Tutor Ale, Hiroko Maruyama, Hidekazu Tamauchi, Jørn D. Mikkelsen and Anne S. Meyer
Article: Fucose-Containing Sulfated Polysaccharides from Brown Seaweeds Inhibit Proliferation of Melanoma Cells and Induce Apoptosis by Activation of Caspase-3 in Vitro
Mar. Drugs 2011, 9(12), 2605-2621; doi:10.3390/md9122605
http://www.mdpi.com/1660-3397/9/12/2605/

Ching-Chyuan Su, Jui-Hsin Su, Jen-Jie Lin, Cheng-Chi Chen, Wen-Ing Hwang, Han Hsiang Huang and Yu-Jen Wu
Article: An Investigation into the Cytotoxic Effects of 13-Acetoxysarcocrassolide from the Soft Coral Sarcophyton crassocaule on Bladder Cancer Cells
Mar. Drugs 2011, 9(12), 2622-2642; doi:10.3390/md9122622
http://www.mdpi.com/1660-3397/9/12/2622/

Priscilla L. Winder, Shirley A. Pomponi and Amy E. Wright
Review: Natural Products from the Lithistida: A Review of the Literature since 2000
Mar. Drugs 2011, 9(12), 2643-2682; doi:10.3390/md9122643
http://www.mdpi.com/1660-3397/9/12/2643/

Asuncion Rocher, Ana Isabel Caceres, Ana Obeso and Constancio Gonzalez
Review: Tetrodotoxin as a Tool to Elucidate Sensory Transduction Mechanisms: The Case for the Arterial Chemoreceptors of the Carotid Body
Mar. Drugs 2011, 9(12), 2683-2704; doi:10.3390/md9122683
http://www.mdpi.com/1660-3397/9/12/2683/

Shih-Tseng Lin, Shang-Kwei Wang and Chang-Yih Duh
Article: Cembranoids from the Dongsha Atoll Soft Coral Lobophytum crassum
Mar. Drugs 2011, 9(12), 2705-2716; doi:10.3390/md9122705
http://www.mdpi.com/1660-3397/9/12/2705/

Charles B. Berde, Umeshkumar Athiraman, Barak Yahalom, David Zurakowski, Gabriel Corfas and Christina Bognet
Article: Tetrodotoxin-Bupivacaine-Epinephrine Combinations for Prolonged Local Anesthesia
Mar. Drugs 2011, 9(12), 2717-2728; doi:10.3390/md9122717
http://www.mdpi.com/1660-3397/9/12/2717/

Aloysio da S. Ferrão-Filho and Betina Kozlowsky-Suzuki
Review: Cyanotoxins: Bioaccumulation and Effects on Aquatic Animals
Mar. Drugs 2011, 9(12), 2729-2772; doi:10.3390/md9122729
http://www.mdpi.com/1660-3397/9/12/2729/

Yang-Chang Wu, Jui-Hsin Su, Tai-Ting Chou, Yin-Pin Cheng, Ching-Feng Weng, Chia-Hung Lee, Lee-Shing Fang, Wei-Hsien Wang, Jan-Jung Li, Mei-Chin Lu, Jimmy Kuo, Jyh-Horng Sheu and Ping-Jyun Sung
Review: Natural Product Chemistry of Gorgonian Corals of Genus Junceella—Part II
Mar. Drugs 2011, 9(12), 2773-2792; doi:10.3390/md9122773
http://www.mdpi.com/1660-3397/9/12/2773/

Kumiko Yokogawa, Isao Matsui-Yuasa, Akiko Tamura, Masaki Terada and Akiko Kojima-Yuasa
Article: Inhibitory Effects of Ecklonia cava Extract on High Glucose-Induced Hepatic Stellate Cell Activation
Mar. Drugs 2011, 9(12), 2793-2808; doi:10.3390/md9122793
http://www.mdpi.com/1660-3397/9/12/2793/

Rihab F. Angawi, Giorgio Bavestrello, Barbara Calcinai, Henny Adeleida Dien, Giovanna Donnarumma, Maria Antonietta Tufano, Iole Paoletti, Elena Grimaldi, Giuseppina Chianese, Ernesto Fattorusso and Orazio Taglialatela-Scafati
Article: Aurantoside J: a New Tetramic Acid Glycoside from Theonella swinhoei. Insights into the Antifungal Potential of Aurantosides
Mar. Drugs 2011, 9(12), 2809-2817; doi:10.3390/md9122809
http://www.mdpi.com/1660-3397/9/12/2809/

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Researcher in marine bioprospecting at the University of Tromsø, Faculty of Biosciences, Fishery and Economics, Norwegian College of Fishery Science – temporary position for 3 years.

Table of Contents:

Leda Giannuzzi, Daniela Sedan, Ricardo Echenique and Dario Andrinolo
Case Report: An Acute Case of Intoxication with Cyanobacteria and Cyanotoxins in Recreational Water in Salto Grande Dam, Argentina
Mar. Drugs 2011, 9(11), 2164-2175; doi:10.3390/md9112164
http://www.mdpi.com/1660-3397/9/11/2164/

Gi-Young Kim, Wun-Jae Kim and Yung Hyun Choi
Review: Pectenotoxin-2 from Marine Sponges: A Potential Anti-Cancer Agent—A Review
Mar. Drugs 2011, 9(11), 2176-2187; doi:10.3390/md9112176
http://www.mdpi.com/1660-3397/9/11/2176/

Renan Oliveira Silva, Geice Maria Pereira dos Santos, Lucas Antonio Duarte Nicolau, Larisse Tavares Lucetti, Ana Paula Macedo Santana, Luciano de Souza Chaves, Francisco Clark Nogueira Barros, Ana Lúcia Ponte Freitas, Marcellus Henrique Loiola Ponte Souza and Jand-Venes Rolim Medeiros
Article: Sulfated-Polysaccharide Fraction from Red Algae Gracilaria caudata Protects Mice Gut Against Ethanol-Induced Damage
Mar. Drugs 2011, 9(11), 2188-2200; doi:10.3390/md9112188
http://www.mdpi.com/1660-3397/9/11/2188/

Oded Bergman, Boaz Mayzel, Matthew A. Anderson, Muki Shpigel, Russell T. Hill and Micha Ilan
Article: Examination of Marine-Based Cultivation of Three Demosponges for Acquiring Bioactive Marine Natural Products
Mar. Drugs 2011, 9(11), 2201-2219; doi:10.3390/md9112201
http://www.mdpi.com/1660-3397/9/11/2201/

Francisco Cen Pacheco, Janny A. Villa-Pulgarin, Faustino Mollinedo, Manuel Norte Martín, José Javier Fernández and Antonio Hernández Daranas
Article: New Polyether Triterpenoids from Laurencia viridis and Their Biological Evaluation
Mar. Drugs 2011, 9(11), 2220-2235; doi:10.3390/md9112220
http://www.mdpi.com/1660-3397/9/11/2220/

Carla Pereira, Yolanda J. Silva, Ana L. Santos, Ângela Cunha, Newton C. M. Gomes and Adelaide Almeida
Article: Bacteriophages with Potential for Inactivation of Fish Pathogenic Bacteria: Survival, Host Specificity and Effect on Bacterial Community Structure
Mar. Drugs 2011, 9(11), 2236-2255; doi:10.3390/md9112236
http://www.mdpi.com/1660-3397/9/11/2236/

Saveetha Kandasamy, Di Fan, Jatinder Singh Sangha, Wajahatullah Khan, Franklin Evans, Alan T. Critchley and Balakrishnan Prithiviraj
Article: Tasco^®, a Product of Ascophyllum nodosum, Imparts Thermal Stress Tolerance in Caenorhabditis elegans
Mar. Drugs 2011, 9(11), 2256-2282; doi:10.3390/md9112256
http://www.mdpi.com/1660-3397/9/11/2256/

Toshiaki J. Hara
Review: Gustatory Detection of Tetrodotoxin and Saxitoxin, and Its Competitive Inhibition by Quinine and Strychnine in Freshwater Fishes
Mar. Drugs 2011, 9(11), 2283-2290; doi:10.3390/md9112283
http://www.mdpi.com/1660-3397/9/11/2283/

Kelvin Sze-Yin Leung, Bonnie Mei-Wah Fong and Yeuk-Ki Tsoi
Review: Analytical Challenges: Determination of Tetrodotoxin in Human Urine and Plasma by LC-MS/MS
Mar. Drugs 2011, 9(11), 2291-2303; doi:10.3390/md9112291
http://www.mdpi.com/1660-3397/9/11/2291/

Ruiyue Yang, Junbo Wang, Zhigang Liu, Xinrong Pei, Xiaolong Han and Yong Li
Article: Antioxidant Effect of a Marine Oligopeptide Preparation from Chum Salmon (Oncorhynchus keta) by Enzymatic Hydrolysis in Radiation Injured Mice
Mar. Drugs 2011, 9(11), 2304-2315; doi:10.3390/md9112304
http://www.mdpi.com/1660-3397/9/11/2304/

Narlize Silva Lira, Ricardo Carneiro Montes, Josean Fechine Tavares, Marcelo Sobral da Silva, Emidio V. L. da Cunha, Petronio Filgueiras de Athayde-Filho, Luis Cezar Rodrigues, Celidarque da Silva Dias and Jose Maria Barbosa-Filho
Review: Brominated Compounds from Marine Sponges of the Genus Aplysina and a Compilation of Their¹³C NMR Spectral Data
Mar. Drugs 2011, 9(11), 2316-2368; doi:10.3390/md9112316
http://www.mdpi.com/1660-3397/9/11/2316/

Adriana Oliveira dos Santos, Elizandra Aparecida Britta, Everson Miguel Bianco, Tania Ueda-Nakamura, Benedito Prado Dias Filho, Renato Crespo Pereira and Celso Vataru Nakamura
Article: 4-Acetoxydolastane Diterpene from the Brazilian Brown Alga Canistrocarpus cervicornis as Antileishmanial Agent
Mar. Drugs 2011, 9(11), 2369-2383; doi:10.3390/md9112369
http://www.mdpi.com/1660-3397/9/11/2369/

Vincent Chung-Him Yu, Peter Hoi-Fu Yu, Kin-Chung Ho and Fred Wang-Fat Lee
Article: Isolation and Identification of a New Tetrodotoxin-Producing Bacterial Species, Raoultella terrigena, from Hong Kong Marine Puffer Fish Takifugu niphobles
Mar. Drugs 2011, 9(11), 2384-2396; doi:10.3390/md9112384
http://www.mdpi.com/1660-3397/9/11/2384/

Jessica Ponder, Byong Hoon Yoo, Adedoyin D. Abraham, Qun Li, Amanda K. Ashley, Courtney L. Amerin, Qiong Zhou, Brian G. Reid, Philip Reigan, Robert Hromas, Jac A. Nickoloff and Daniel V. LaBarbera
Article: Neoamphimedine Circumvents Metnase-Enhanced DNA Topoisomerase IIα Activity Through ATP-Competitive Inhibition
Mar. Drugs 2011, 9(11), 2397-2408; doi:10.3390/md9112397
http://www.mdpi.com/1660-3397/9/11/2397/

Matti Vornanen, Minna Hassinen and Jaakko Haverinen
Article: Tetrodotoxin Sensitivity of the Vertebrate Cardiac Na⁺ Current
Mar. Drugs 2011, 9(11), 2409-2422; doi:10.3390/md9112409
http://www.mdpi.com/1660-3397/9/11/2409/

Samuel Abbas, Michelle Kelly, John Bowling, James Sims, Amanda Waters and Mark Hamann
Review: Advancement into the Arctic Region for Bioactive Sponge Secondary Metabolites
Mar. Drugs 2011, 9(11), 2423-2437; doi:10.3390/md9112423
http://www.mdpi.com/1660-3397/9/11/2423/

Dioli Ann Payo, Joannamel Colo, Hilconida Calumpong and Olivier de Clerck
Article: Variability of Non-Polar Secondary Metabolites in the Red Alga Portieria
Mar. Drugs 2011, 9(11), 2438-2468; doi:10.3390/md9112438
http://www.mdpi.com/1660-3397/9/11/2438/

Simon P. B. Ovenden, Jonathan L. Nielson, Catherine H. Liptrot, Richard H. Willis, Dianne M. Tapiolas, Anthony D. Wright and Cherie A. Motti
Short Note: A New Diketopiperazine, Cyclo-(4-S-hydroxy-R-proline-R-isoleucine), from an Australian Specimen of the Sponge Stelletta sp.
Mar. Drugs 2011, 9(11), 2469-2478; doi:10.3390/md9112469
http://www.mdpi.com/1660-3397/9/11/2469/

Cheng-Hai Gao, Yi-Fei Wang, Shen Li, Pei-Yuan Qian and Shu-Hua Qi
Article: Alkaloids and Sesquiterpenes from the South China Sea Gorgonian Echinogorgia pseudossapo
Mar. Drugs 2011, 9(11), 2479-2487; doi:10.3390/md9112479
http://www.mdpi.com/1660-3397/9/11/2479/

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The Canadian facility has a battery of reactors and support utilities that enable it to operate multi-tonne scale fermentations under industrial conditions. During the project it produced sufficient biomass for Photonz to complete development of the downstream purification processes for its EPA product, also at pilot industrial scale.

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a new scientific commercialization venture in eastern North Carolina.  The CEO requires a hands-on leader to work with the local, national, and global biotechnology communities and research institutions for collaboration in the development of both academic and commercial opportunities, related to marine biotechnology.

The ideal Chief Executive candidate will effectively create, engage, inform, and communicate with a marine biotechnology network, ranging from universities to businesses and state leaders. The goal is to successfully cultivate collaborative innovation and accelerate North Carolina’s bioscience research engine to deliver economic benefits statewide.

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He was speaking at a one-day seminar on the issue held in the institute. He said technology was available to make full use of fisheries waste and manufacture these valuable by-products. He said it was estimated that about 8.5 million tonnes of fisheries was being generated in the country and shrimp processing was one of the largest sources of industrial fish waste, with more than one lakh tonnes. Business worth Rs. 3,00,000 crores could be generated out of the waste, but at present there were hardly 38 units or so in the country.

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Table of Contents:

Shi-Yie Cheng, Pei-Wen Chen, Hwa-Pyng Chen, Shang-Kwei Wang and Chang-Yih Duh
Article: New Cembranolides from the Dongsha Atoll Soft Coral Lobophytum durum
Mar. Drugs 2011, 9(8), 1307-1318; doi:10.3390/md9081307
http://www.mdpi.com/1660-3397/9/81307/

Chia-Ying Kao, Jui-Hsin Su, Mei-Chin Lu, Tsong-Long Hwang, Wei-Hsien Wang, Jih-Jung Chen, Jyh-Horng Sheu, Yueh-Hsiung Kuo, Ching-Feng Weng, Lee-Shing Fang, Zhi-Hong Wen and Ping-Jyun Sung
Article: Lobocrassins A–E: New Cembrane-Type Diterpenoids from the Soft Coral Lobophytum crassum
Mar. Drugs 2011, 9(8), 1319-1331; doi:10.3390/md9081319
http://www.mdpi.com/1660-3397/9/81319/

Mariana Angelica Oliveira Bitencourt, Gracielle Rodrigues Dantas, Daysianne Pereira Lira, Jose Maria Barbosa-Filho, George Emmanuel Cavalcanti de Miranda, Barbara Viviana de Oliveira Santos and Janeusa Trindade Souto
Article: Aqueous and Methanolic Extracts of Caulerpa mexicana Suppress Cell Migration and Ear Edema Induced by Inflammatory Agents
Mar. Drugs 2011, 9(8), 1332-1345; doi:10.3390/md9081332
http://www.mdpi.com/1660-3397/9/81332/

Laura de Andrade Moura, Fredy Ortiz-Ramirez, Diana Negrao Cavalcanti, Suzi Meneses Ribeiro, Guilherme Muricy, Valeria Laneuville Teixeira and Andre Lopes Fuly
Article: Evaluation of Marine Brown Algae and Sponges from Brazil as Anticoagulant and Antiplatelet Products
Mar. Drugs 2011, 9(8), 1346-1358; doi:10.3390/md9081346
http://www.mdpi.com/1660-3397/9/81346/

Min-Kyoung Park, Uhee Jung and Changhyun Roh
Article: Fucoidan from Marine Brown Algae Inhibits Lipid Accumulation
Mar. Drugs 2011, 9(8), 1359-1367; doi:10.3390/md9081359
http://www.mdpi.com/1660-3397/9/81359/

Yi Wang, Jinkai Zheng, Peipei Liu, Wei Wang and Weiming Zhu
Communication: Three New Compounds from Aspergillus terreus PT06-2 Grown in a High Salt Medium
Mar. Drugs 2011, 9(8), 1368-1378; doi:10.3390/md9081368
http://www.mdpi.com/1660-3397/9/81368/

Ya-Nan Wang, Chang-Lun Shao, Cai-Juan Zheng, Yi-Yan Chen and Chang-Yun Wang
Article: Diversity and Antibacterial Activities of Fungi Derived from the Gorgonian Echinogorgia rebekka from the South China Sea
Mar. Drugs 2011, 9(8), 1379-1390; doi:10.3390/md9081379
http://www.mdpi.com/1660-3397/9/81379/

Anahit Penesyan, Jan Tebben, Matthew Lee, Torsten Thomas, Staffan Kjelleberg, Tilmann Harder and Suhelen Egan
Article: Identification of the Antibacterial Compound Produced by the Marine Epiphytic Bacterium Pseudovibrio sp. D323 and Related Sponge-Associated Bacteria
Mar. Drugs 2011, 9(8), 1391-1402; doi:10.3390/md9081391
http://www.mdpi.com/1660-3397/9/81391/

Cui Li, Ming-Ping La, Peng Sun, Tibor Kurtan, Attila Mandi, Hua Tang, Bao-Shu Liu, Yang-Hua Yi, Ling Li and Wen Zhang
Article: Bioactive (3Z,5E)-11,20-Epoxybriara-3,5-dien-7,18-olide Diterpenoids from the South China Sea Gorgonian Dichotella gemmacea
Mar. Drugs 2011, 9(8), 1403-1418; doi:10.3390/md9081403
http://www.mdpi.com/1660-3397/9/81403/

Takashi Maoka, Naoshige Akimoto, Miyuki Tsushima, Sadao Komemushi, Takuma Mezaki, Fumihito Iwase, Yoshimitsu Takahashi, Naomi Sameshima, Miho Mori and Yoshikazu Sakagami
Article: Carotenoids in Marine Invertebrates Living along the Kuroshio Current Coast
Mar. Drugs 2011, 9(8), 1419-1427; doi:10.3390/md9081419
http://www.mdpi.com/1660-3397/9/81419/

Sumei Li, Xinpeng Tian, Siwen Niu, Wenjun Zhang, Yuchan Chen, Haibo Zhang, Xianwen Yang, Weimin Zhang, Wenjun Li, Si Zhang, Jianhua Ju and Changsheng Zhang
Article: Pseudonocardians A–C, New Diazaanthraquinone Derivatives from a Deap-Sea Actinomycete Pseudonocardia sp. SCSIO 01299
Mar. Drugs 2011, 9(8), 1428-1439; doi:10.3390/md9081428
http://www.mdpi.com/1660-3397/9/81428/

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Dasycladus vermicularis is a green alga found in warm tropical waters. Intriguingly, it is unicellular – the entire organism, which can be more than 2cm long, is a single cell. This makes it especially vulnerable to external damage, with the danger that much of its contents would leak out. To avoid this, the organism has evolved a way of rapidly plugging any breach with a tough biopolymer consisting of cross-linked protein and carbohydrate molecules. Within seconds of any damage the wound starts sealing, and within minutes it is completely healed.

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