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NineSigma Seeks Natural Compound Collections for Screening: invites proposals for the purchase of natural compound collections
Posted On: February 21, 2011NineSigma reports that they are looking for proposals for the purchase of natural compound collections for screening. The compounds may be pure or extracts (fractionated or not) or semi-synthetic but must be derived from sustainable natural sources. They are interested in compound collection acquisition, licensing, supplier agreement. Co-development of any discovered activities is also possible.
Description
Collection(s) will be screened in assays relevant to the development of consumer care products. As such, compounds should be potentially suitable for such applications and must either be currently available or have a reasonable likelihood of being available on sustainable commercial scales (tons).
Possible approaches:
- Samples may be pure or semi-pure, including extracts (preferably fractionated).
- Among others, libraries of commodity natural products, natural product components, and consumer care ingredients are all possible sample sources.
- Developing nations with unique biota that could be sustainably developed may present with interesting avenues of investigation.
- Low, medium, and/or high molecular weight compounds are all of interest provided they are derived from acceptable natural sources.
Approaches not of interest:
- Synthetic chemical libraries
- Collections of pharmaceutical drugs
- Compounds derived from animal sources unless they are obtained “without harm”
- Biological agents
- Compounds or extracts that cannot be supplied (or potentially supplied) on sustainable commercial scales.
Publication: Marine-derived functional ingredients as potential antioxidants in the food industry–An overview
Posted On: February 17, 2011Dai-Hung Ngo, Isuru Wijesekara, Thanh-Sang Vo, Quang Van Ta and Se-Kwon Kim
Abstract
Recently, a great deal of interest has been developed by the consumers towards natural bioactive compounds as functional ingredients in the food products due to their various health beneficial effects. Hence, it can be suggested that antioxidative functional ingredients from marine foods and their by-products are alternative sources for synthetic ingredients that can contribute to a consumer’s well-being, as a part of nutraceuticals and functional foods. This contribution presents an overview of the marine food-derived antioxidants such as bioactive peptides, chitooligosaccharide derivatives, sulfated polysaccharides, phlorotannins and carotenoids with the potential utilization in the food industry.
SAMS and Aquapharm sign marine products agreement
Posted On: November 30, 2010AQUAPHARM Biodiscovery, a leading marine biotechnology company, has announced it has signed a long-term agreement with the Scottish Association for Marine Science (SAMS) to discover, develop and launch new marine products derived from marine micro-organisms.
Under the terms of this agreement, SAMS will provide Aquapharm with privileged access to the vast array of marine samples that it has collected from diverse marine habitats around the globe. Aquapharm will then apply its extensive culturing and marine fermentation know-how to these samples to capture and harness the full microbial biodiversity that they contain, further expanding the scope of its collection of marine micro-organisms.
Once Aquapharm has cultured and identified the range of novel microbial species present in these samples, it will draw out their unique biochemistry through the application of its suite of screening technologies, including SeaRch™, in some cases activating otherwise inaccessible, dormant biosynthetic pathways to produce a cocktail of chemical diversity that Aquapharm will convert into candidate functional ingredients or pharmaceuticals.
US: Newsweek Magazine showcases hunt for medical cures underwater
Posted On: November 24, 2010Advances in technology are making it easier and increasingly profitable to hunt for drugs in the ocean. Marine bioprospectors, as they’re known, are scouring coral reefs, deep-sea trenches, and everything in between. David Newman, chief of the natural products branch at the National Cancer Institute (NCI), estimates that at least 30 research teams are experimenting with marine-derived compounds for treating cancer, neural degenerative diseases like Alzheimer’s and Parkinson’s, malaria, diabetes, depression, asthma, and other ailments.
Nature Nova Signs MoU With Jefi Biomarine On Aqua Technology
Posted On: November 3, 2010Nature Nova Sdn Bhd, a subsidiary of Germany’s NatureNova GmBh, today signed a memorandum of understanding (MoU) with JEFI BioMarine Sdn Bhd, a subsidiary of Jeenhuat Foodstuffs Industries Sdn Bhd (JEFI).
“The memorandum will see both companies collaborating in the research and development of aqua technology, shrimp farming and hatchery,” JEFI said in a statement Tuesday.
The research will be conducted by JEFI’s High Tech Marine Life Sciences Research and Development Centre which is located at the Penang Halal Science Park.
The MoU was signed at the BioMalaysia Conference 2010 here which also saw an MoU between University of Manchester, Lonza AG and Sabah Biodiversity Centre, and a memorandum of agreement (MoA) between Furley Bioextract Sdn Bhd with Koperasi Shamelin Bhd.
The MoU involving the University of Manchester, Lonza AG and Sabah Biodiversity Centre is on a marine bioprospecting project in search of novel fluorescent proteins and enzymes as part of the Lonza Innovation for Future Technology initiatives.
Aqua Bio Technology: ABT signs Supply Agreement for Asian Markets
Posted On: September 30, 2010Aqua Bio Technology (Oslo Axess : ABT) a Norwegian marine biotech firm developing, producing and selling patented marine based ingredients and technologies to the international cosmetic and skin care industry, today announced it has entered into a sales agreement of with a highly regarded Asian manufacturer of skin care products. As a part of the agreement, ABT will supply its bioactive ingredient Zonase X(TM) to be the key ingredient in a new product line the manufacturer will launch in January 2011.
The new line will consist of five products, developed in collaboration with ABT. The new skin care line will initially be introduced in the Asian markets through the manufacturer’s existing distribution channels. In addition, the manufacturer is also in discussion with distributors in Australia and selected European countries regarding launch in those markets.
Due to competitive reasons, the manufacturer has requested that it is not named until the products are launched. The reason is that the manufacturer considers Zonase X(TM) a novel and highly innovative technology.
ABT Strengthens Organization With The Appointment of New CEO and Sales Management
Posted On: September 15, 2010Norwegian marine biotechnology company Aqua Bio Technology ASA (ABT) has strengthened its organization, and has secured valuable competence for the company’s further growth and commercial development with the appointment of Arvid Lindberg as the new CEO, and Fanny Fagot-Coste as the Head of sales and Product Development.
Arvid Lindberg (37) takes the role as ABT’s new CEO. He holds a degree in economics from the Norwegian School of Economics and Business Administration in Bergen and comes from the position as Business Unit Director in Roche.
On the sales and product development side, the company has hired Fanny Fagot-Coste (31) as the new Sales Manager Asia /Head of Product Development. Fanny is French and has a double Masters degree in Bioengineering and Cosmetology (Honours) from Universite de Technologie de Compiegne (UTC) and Universite Paris XI, Faculty of Pharmacy.
5th International Conference on Marine Bioprospecting in Tromso; 23-25th February 2011
Posted On: August 4, 2010BIOPROSP is a leading international biennial conference series on bioprospecting from cold marine environments. These conferences aim to present explorative research and its industrial applications in an integrated fashion.
The focus in the 2011 conference will be industrial biotech and bioprospecting as a stepping stone towards the bioeconomy.
Target group: Academic and industry researchers, decision makers, regulatory experts, investors and public facilitators.
A number of interesting speakers from the USA, Russia, UK, Denmark, Switzerland and Norway have been invited. In addition there will be a half day pre-conference workshop: ‘Addressing industrial applications’ on 23 February 2011
Delegates are invited to participate with poster presentations, and a number of posters will be selected for oral presentation.
MDPI Publishes New Marine Drugs Issue: Volume 8, Issue 6
Posted On: July 22, 2010MDPI AG announce the publication of the following issue: Mar.
Drugs, Volume 8, Issue 6 (June 2010), Pages 1731-1961 at
http://www.mdpi.com/1660-3397/8/6/
Table of Contents:
Sonia de Caralt, Javier Sánchez-Fontenla, María J. Uriz and Rene H.
Wijffels
Article: In Situ Aquaculture Methods for Dysidea avara (Demospongiae,
Porifera) in the Northwestern Mediterranean
Mar. Drugs 2010, 8(6), 1731-1742; doi:10.3390/md8061731
http://www.mdpi.com/1660-3397/8/6/1731
Charles Santhanaraju Vairappan, Takahiro Ishii, Tan Kai Lee, Minoru Suzuki
and Zhan Zhaoqi
Article: Antibacterial Activities of a New Brominated Diterpene from
Borneon Laurencia spp.
Mar. Drugs 2010, 8(6), 1743-1749; doi:10.3390/md8061743
http://www.mdpi.com/1660-3397/8/6/1743
Ruth Harris, Elena Lecumberri and Angeles Heras
Article: Chitosan-Genipin Microspheres for the Controlled Release of
Drugs: Clarithromycin, Tramadol and Heparin
Mar. Drugs 2010, 8(6), 1750-1762; doi:10.3390/md8061750
http://www.mdpi.com/1660-3397/8/6/1750
João C. Fernandes, Humberto Spindola, Vanessa de Sousa, Alice
Santos-Silva, Manuela E. Pintado, Francisco Xavier Malcata and João E.
Carvalho
Communication: Anti-Inflammatory Activity of Chitooligosaccharides in Vivo
Mar. Drugs 2010, 8(6), 1763-1768; doi:10.3390/md8061763
http://www.mdpi.com/1660-3397/8/6/1763
Xiaomei Wei, Tim S. Bugni, Mary Kay Harper, Imelda T. Sandoval, Elizabeth
J. Manos, Jennifer Swift, Ryan M. Van Wagoner, David A. Jones and Chris M.
Ireland
Article: Evaluation of Pyridoacridine Alkaloids in a Zebrafish Phenotypic
Assay
Mar. Drugs 2010, 8(6), 1769-1778; doi:10.3390/md8061769
http://www.mdpi.com/1660-3397/8/6/1769
Annarita Poli, Gianluca Anzelmo and Barbara Nicolaus
Review: Bacterial Exopolysaccharides from Extreme Marine Habitats:
Production, Characterization and Biological Activities
Mar. Drugs 2010, 8(6), 1779-1802; doi:10.3390/md8061779
http://www.mdpi.com/1660-3397/8/6/1779
Susan Matthew, Ranjala Ratnayake, Mikel A. Becerro, Raphael
Ritson-Williams, Valerie J. Paul and Hendrik Luesch
Article: Intramolecular Modulation of Serine Protease Inhibitor Activity
in a Marine Cyanobacterium with Antifeedant Properties
Mar. Drugs 2010, 8(6), 1803-1816; doi:10.3390/md8061803
http://www.mdpi.com/1660-3397/8/6/1803
Li Liu and Kathleen S. Rein
Review: New Peptides Isolated from Lyngbya Species: A Review
Mar. Drugs 2010, 8(6), 1817-1837; doi:10.3390/md8061817
http://www.mdpi.com/1660-3397/8/6/1817
Amandine Caillaud, Pablo de la Iglesia, H. Taiana Darius, Serge Pauillac,
Katerina Aligizaki, Santiago Fraga, Mireille Chinain and Jorge Diogène
Review: Update on Methodologies Available for Ciguatoxin Determination:
Perspectives to Confront the Onset of Ciguatera Fish Poisoning in Europe
Mar. Drugs 2010, 8(6), 1838-1907; doi:10.3390/md8061838
http://www.mdpi.com/1660-3397/8/6/1838
Bárbara Frazão, Rosário Martins and Vitor Vasconcelos
Article: Are Known Cyanotoxins Involved in the Toxicity of Picoplanktonic
and Filamentous North Atlantic Marine Cyanobacteria?
Mar. Drugs 2010, 8(6), 1908-1919; doi:10.3390/md8061908
http://www.mdpi.com/1660-3397/8/6/1908
Chen Zhang and Se-Kwon Kim
Review: Research and Application of Marine Microbial Enzymes: Status and
Prospects
Mar. Drugs 2010, 8(6), 1920-1934; doi:10.3390/md8061920
http://www.mdpi.com/1660-3397/8/6/1920
Christine J. Band-Schmidt, José J. Bustillos-Guzmán, David J.
López-Cortés, Ismael Gárate-Lizárraga, Erick J. Núñez-Vázquez and
Francisco E. Hernández-Sandoval
Review: Ecological and Physiological Studies of Gymnodinium catenatum in
the Mexican Pacific: A Review
Mar. Drugs 2010, 8(6), 1935-1961; doi:10.3390/md8061935
http://www.mdpi.com/1660-3397/8/6/1935
Bioprocessing Data for the Production of Marine Enzymes Now Available
Posted On: May 21, 2010Abstract: This review is a synopsis of different bioprocess engineering approaches adopted for the production of marine enzymes. Three major modes of operation: batch, fed-batch and continuous have been used for production of enzymes (such as protease, chitinase, agarase, peroxidase) mainly from marine bacteria and fungi on a laboratory bioreactor and pilot plant scales. Submerged, immobilized and solid-state processes in batch mode were widely employed. The fed-batch process was also applied in several bioprocesses. Continuous processes with suspended cells as well as with immobilized cells have been used. Investigations in shake flasks were conducted with the prospect of large-scale processing in reactors.
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