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Marine enzyme can decongest sinusitis
Posted On: February 24, 2013A new nasal spray from a marine microbe will help clear chronic sinusitis, which causes nasal congestion, difficulty in breathing, pain and swelling around your eyes and cheeks. A team of scientists and surgeons from Newcastle University are developing the spray with an enzyme isolated from a marine bug Bacillus licheniformis, found on the surface of seaweed.
Lab experiments showed that the enzyme, called NucB, dispersed 58 per cent of biofilms in chronic sinusitis formed by the marine bug. The biofilm acts as a slimy barrier to protect bugs from sprays or antibiotics, the journal Public Library of Science ONE reports.
MDPI announces availability of Mar. Drugs, Volume 10, Issue 9 (September 2012), Pages Pages 1899-2137
Posted On: October 14, 2012MDPI announces availability of Mar. Drugs, Volume 10, Issue 9 (September 2012), Pages Pages 1899-2137
http://www.mdpi.com/1660-3397/10/9/
Table of Contents:
Shi-Ying Huang, Nan-Fu Chen, Wu-Fu Chen, Han-Chun Hung, Hsin-Pai Lee, Yen-You Lin, Hui-Min Wang, Ping-Jyun Sung, Jyh-Horng Sheu and Zhi-Hong Wen
Article: Sinularin from Indigenous Soft Coral Attenuates Nociceptive Responses and Spinal Neuroinflammation in Carrageenan-Induced Inflammatory Rat Model
Mar. Drugs 2012, 10(9), 1899-1919; doi:10.3390/md10091899
http://www.mdpi.com/1660-3397/10/9/1899/
Hugo Pereira, Luísa Barreira, Filipe Figueiredo, Luísa Custódio, Catarina Vizetto-Duarte, Cristina Polo, Eva Rešek, Aschwin Engelen and João Varela
Article: Polyunsaturated Fatty Acids of Marine Macroalgae: Potential for Nutritional and Pharmaceutical Applications
Mar. Drugs 2012, 10(9), 1920-1935; doi:10.3390/md10091920
http://www.mdpi.com/1660-3397/10/9/1920/
Luiz Gonzaga do Nascimento-Neto, Romulo Farias Carneiro, Suzete Roberta da Silva, Bruno Rocha da Silva, Francisco Vassiliepe Sousa Arruda, Victor Alves Carneiro, Kyria Santiago do Nascimento, Silvana Saker-Sampaio, Valdemiro Amaro da Silva, Ana Lúcia Figueiredo Porto, Benildo Sousa Cavada, Alexandre Holanda Sampaio, Edson Holanda Teixeira and Celso Shiniti Nagano
Article: Characterization of Isoforms of the Lectin Isolated from the Red Algae Bryothamnion seaforthii and Its Pro-Healing Effect
Mar. Drugs 2012, 10(9), 1936-1954; doi:10.3390/md10091936
http://www.mdpi.com/1660-3397/10/9/1936/
Inmaculada Couso, Baldo F. Cordero, María Ángeles Vargas and Herminia Rodríguez
Article: Efficient Heterologous Transformation of Chlamydomonas reinhardtii npq2 Mutant with the Zeaxanthin Epoxidase Gene Isolated and Characterized from Chlorella zofingiensis
Mar. Drugs 2012, 10(9), 1955-1976; doi:10.3390/md10091955
http://www.mdpi.com/1660-3397/10/9/1955/
Luiz Henrique Agra Cavalcante-Silva, Carolina Barbosa Brito da Matta, Morgana Vital de Araújo, José Maria Barbosa-Filho, Daysianne Pereira de Lira, Bárbara Viviana de Oliveira Santos, George Emmanuel C. de Miranda and Magna Suzana Alexandre-Moreira
Article: Antinociceptive and Anti-Inflammatory Activities of Crude Methanolic Extract of Red AlgaBryothamnion triquetrum
Mar. Drugs 2012, 10(9), 1977-1992; doi:10.3390/md10091977
http://www.mdpi.com/1660-3397/10/9/1977/
Wen-Li Mei, Bo Zheng, You-Xing Zhao, Hui-Ming Zhong, Xun-Li Wu Chen, Yan-Bo Zeng, Wen-Hua Dong, Jiu-Li Huang, Peter Proksch and Hao-Fu Dai
Article: Meroterpenes from Endophytic Fungus A1 of Mangrove Plant Scyphiphora hydrophyllacea
Mar. Drugs 2012, 10(9), 1993-2001; doi:10.3390/md10091993
http://www.mdpi.com/1660-3397/10/9/1993/
Nednaldo Dantas-Santos, Jailma Almeida-Lima, Arthur Anthunes Jacome Vidal, Dayanne Lopes Gomes, Ruth Medeiros Oliveira, Silvia Santos Pedrosa, Paula Pereira, Francisco Miguel Gama and Hugo Alexandre Oliveira Rocha
Article: Antiproliferative Activity of Fucan Nanogel
Mar. Drugs 2012, 10(9), 2002-2022; doi:10.3390/md10092002
http://www.mdpi.com/1660-3397/10/9/2002/
Bin Yang, Xuefeng Zhou, Hui Huang, Xian-Wen Yang, Juan Liu, Xiuping Lin, Xiubao Li, Yan Peng and Yonghong Liu
Article: New Cembrane Diterpenoids from a Hainan Soft Coral Sinularia sp.
Mar. Drugs 2012, 10(9), 2023-2032; doi:10.3390/md10092023
http://www.mdpi.com/1660-3397/10/9/2023/
Beatriz Martínez-Poveda, Salvador Rodríguez-Nieto, Melissa García-Caballero, Miguel-Ángel Medina and Ana R. Quesada
Article: The Antiangiogenic Compound Aeroplysinin-1 Induces Apoptosis in Endothelial Cells by Activating the Mitochondrial Pathway
Mar. Drugs 2012, 10(9), 2033-2046; doi:10.3390/md10092033
http://www.mdpi.com/1660-3397/10/9/2033/
Orri Thor Ormarsson, Thormodur Geirsson, Einar Stefan Bjornsson, Tomas Jonsson, Pall Hegli Moller, Thorsteinn Loftsson and Einar Stefansson
Article: Clinical Trial: Marine Lipid Suppositories as Laxatives
Mar. Drugs 2012, 10(9), 2047-2054; doi:10.3390/md10092047
http://www.mdpi.com/1660-3397/10/9/2047/
Jun Wang, Shihui Chen, Shiqiang Xu, Xing Yu, Dongqing Ma, Xiamin Hu and Xiaolu Cao
Article: In Vivo Induction of Apoptosis by Fucoxanthin, a Marine Carotenoid, Associated with Down-Regulating STAT3/EGFR Signaling in Sarcoma 180 (S180) Xenografts-Bearing Mice
Mar. Drugs 2012, 10(9), 2055-2068; doi:10.3390/md10092055
http://www.mdpi.com/1660-3397/10/9/2055/
Baldo F. Cordero, Inmaculada Couso, Rosa Leon, Herminia Rodriguez and Maria Angeles Vargas
Article: Isolation and Characterization of a Lycopene ε-Cyclase Gene of Chlorella (Chromochloris)zofingiensis. Regulation of the Carotenogenic Pathway by Nitrogen and Light
Mar. Drugs 2012, 10(9), 2069-2088; doi:10.3390/md10092069
http://www.mdpi.com/1660-3397/10/9/2069/
Michael Anthony Timmers, Daniel Anthony Dias and Sylvia Urban
Short Note: Application of HPLC-NMR in the Identification of Plocamenone and Isoplocamenone from the Marine Red Alga Plocamium angustum
Mar. Drugs 2012, 10(9), 2089-2102; doi:10.3390/md10092089
http://www.mdpi.com/1660-3397/10/9/2089/
Shang-Kwei Wang, Tsun-Tai Yeh and Chang-Yih Duh
Article: Briacavatolides D–F, New Briaranes from the Taiwanese Octocoral Briareum excavatum
Mar. Drugs 2012, 10(9), 2103-2110; doi:10.3390/md10092103
http://www.mdpi.com/1660-3397/10/9/2103/
Ruth F. Guillermo, Xiaoying Zhang, Radhey S. Kaushik, David Zeman, Safwat A. Ahmed, Sherief Khalifa, Hesham Fahmy and Chandradhar Dwivedi
Article: Dose-Response on the Chemopreventive Effects of Sarcophine-Diol on UVB-Induced Skin Tumor Development in SKH-1 Hairless Mice
Mar. Drugs 2012, 10(9), 2111-2125; doi:10.3390/md10092111
http://www.mdpi.com/1660-3397/10/9/2111/
Yoonyeong Lee, Kyoung Hwa Jang, Ju-eun Jeon, Woo-Young Yang, Chung J. Sim, Ki-Bong Oh and Jongheon Shin
Article: Cyclic Bis-1,3-dialkylpyridiniums from the Sponge Haliclona sp.
Mar. Drugs 2012, 10(9), 2126-2137; doi:10.3390/md10092126
http://www.mdpi.com/1660-3397/10/9/2126/
PharmaMar and Costa Rica to search ocean in search of cancer cures
Posted On: October 14, 2012Experts from Costa Rica and the Spanish company PharmaMar, dedicated to marine biotechnology research, beginning in February will seek new cures and treatments for cancer in organisms living in Costa Rican waters.
The Spanish company will work for five years in the territorial waters of Costa Rica thanks to an agreement with the National Institute of Biodiversity (INBio), promoted by the Ministry of Foreign Trade (Comex).
A spokesman of the INBio explained that the Costa Rican and Spanish specialists will develop innovative studies on macro-organisms, especially sponges, both in the Pacific as well as the Caribbean to support the discovery of innovative drugs with anti-tumor activity.
The director general of the Institute, Carlos Hernandez, said in a statement that the agreement, signed last September, enables both organizations to work together and to the mutual exchange of knowledge, each in their specialty.
Mar. Drugs, Volume 10, Issue 8 (August 2012), Pages 1619-1898 Newly Released
Posted On: August 30, 2012MDPI is pleased to announce the publication of the following issue:
Mar. Drugs, Volume 10, Issue 8 (August 2012), Pages Pages 1619-1898
TOC:
Anthony D. Wright, Jonathan L. Nielson, Dianne M. Tapiolas, Catherine H. Liptrot and Cherie A. Motti
Article: A Great Barrier Reef Sinularia sp. Yields Two New Cytotoxic Diterpenes
Mar. Drugs 2012, 10(8), 1619-1630; doi:10.3390/md10081619
http://www.mdpi.com/1660-3397/10/8/1619/
Vânia Cristina Desoti, Danielle Lazarin-Bidóia, Daniela Bueno Sudatti, Renato Crespo Pereira, Antonio Alonso, Tania Ueda-Nakamura, Benedito Prado Dias Filho, Celso Vataru Nakamura and Sueli de Oliveira Silva
Article: Trypanocidal Action of (−)-Elatol Involves an Oxidative Stress Triggered by Mitochondria Dysfunction
Mar. Drugs 2012, 10(8), 1631-1646; doi:10.3390/md10081631
http://www.mdpi.com/1660-3397/10/8/1631/
Na Gao, Mingyi Wu, Shao Liu, Wu Lian, Zi Li and Jinhua Zhao
Article: Preparation and Characterization of O-Acylated Fucosylated Chondroitin Sulfate from Sea Cucumber
Mar. Drugs 2012, 10(8), 1647-1661; doi:10.3390/md10081647
http://www.mdpi.com/1660-3397/10/8/1647/
Rian J. Meginley, Prasoon Gupta, Thomas C. Schulz, Amanda B. McLean, Allan J. Robins and Lyndon M. West
Article: Briareolate Esters from the Gorgonian Briareum asbestinum
Mar. Drugs 2012, 10(8), 1662-1670; doi:10.3390/md10081662
http://www.mdpi.com/1660-3397/10/8/1662/
Vladimir I. Kalinin, Natalia V. Ivanchina, Vladimir B. Krasokhin, Tatyana N. Makarieva and Valentin A. Stonik
Review: Glycosides from Marine Sponges (Porifera, Demospongiae): Structures, Taxonomical Distribution, Biological Activities and Biological Roles
Mar. Drugs 2012, 10(8), 1671-1710; doi:10.3390/md10081671
http://www.mdpi.com/1660-3397/10/8/1671/
Malcolm W. B. McCulloch, Brad Haltli, Douglas H. Marchbank and Russell G. Kerr
Article: Evaluation of Pseudopteroxazole and Pseudopterosin Derivatives against Mycobacteriumtuberculosis and Other Pathogens
Mar. Drugs 2012, 10(8), 1711-1728; doi:10.3390/md10081711
http://www.mdpi.com/1660-3397/10/8/1711/
Nikolaj G. Vynne, Maria Mansson and Lone Gram
Article: Gene Sequence Based Clustering Assists in Dereplication of Pseudoalteromonas luteoviolacea Strains with Identical Inhibitory Activity and Antibiotic Production
Mar. Drugs 2012, 10(8), 1729-1740; doi:10.3390/md10081729
http://www.mdpi.com/1660-3397/10/8/1729/
Laura Núñez-Pons, Marianna Carbone, Jennifer Vázquez, Jaime Rodríguez, Rosa María Nieto, María Mercedes Varela, Margherita Gavagnin and Conxita Avila
Article: Natural Products from Antarctic Colonial Ascidians of the Genera Aplidium and Synoicum: Variability and Defensive Role
Mar. Drugs 2012, 10(8), 1741-1764; doi:10.3390/md10081741
http://www.mdpi.com/1660-3397/10/8/1741/
Conceição Egas, Miguel Pinheiro, Paula Gomes, Cristina Barroso and Raul Bettencourt
Article: The Transcriptome of Bathymodiolus azoricus Gill Reveals Expression of Genes from Endosymbionts and Free-Living Deep-Sea Bacteria
Mar. Drugs 2012, 10(8), 1765-1783; doi:10.3390/md10081765
http://www.mdpi.com/1660-3397/10/8/1765/
Eliseu Rodrigues, Lilian R. B. Mariutti and Adriana Z. Mercadante
Article: Scavenging Capacity of Marine Carotenoids against Reactive Oxygen and Nitrogen Species in a Membrane-Mimicking System
Mar. Drugs 2012, 10(8), 1784-1798; doi:10.3390/md10081784
http://www.mdpi.com/1660-3397/10/8/1784/
Genoveffa Nuzzo, Maria Letizia Ciavatta, Robert Kiss, Véronique Mathieu, Helene Leclercqz, Emiliano Manzo, Guido Villani, Ernesto Mollo, Florence Lefranc, Lisette D’Souza, Margherita Gavagnin and Guido Cimino
Article: Chemistry of the Nudibranch Aldisa andersoni: Structure and Biological Activity of Phorbazole Metabolites
Mar. Drugs 2012, 10(8), 1799-1811; doi:10.3390/md10081799
http://www.mdpi.com/1660-3397/10/8/1799/
Bárbara Frazão, Vitor Vasconcelos and Agostinho Antunes
Review: Sea Anemone (Cnidaria, Anthozoa, Actiniaria) Toxins: An Overview
Mar. Drugs 2012, 10(8), 1812-1851; doi:10.3390/md10081812
http://www.mdpi.com/1660-3397/10/8/1812/
Shu-Ping Wu, Tsui-Chin Huang, Ching-Chun Lin, Cho-Fat Hui, Cheng-Hui Lin and Jyh-Yih Chen
Article: Pardaxin, a Fish Antimicrobial Peptide, Exhibits Antitumor Activity toward Murine Fibrosarcoma in Vitro and in Vivo
Mar. Drugs 2012, 10(8), 1852-1872; doi:10.3390/md10081852
http://www.mdpi.com/1660-3397/10/8/1852/
Tomohiro Osaki, Kazuo Azuma, Seiji Kurozumi, Yoshimori Takamori, Takeshi Tsuka, Tomohiro Imagawa, Yoshiharu Okamoto and Saburo Minami
Article: Metabolomic Analyses of Blood Plasma after Oral Administration of D-Glucosamine Hydrochloride to Dogs
Mar. Drugs 2012, 10(8), 1873-1882; doi:10.3390/md10081873
http://www.mdpi.com/1660-3397/10/8/1873/
Tzu-Rong Su, Feng-Jen Tsai, Jen-Jie Lin, Han Hsiang Huang, Chien-Chih Chiu, Jui-Hsin Su, Ya-Ting Yang, Jeff Yi-Fu Chen, Bing-Sang Wong and Yu-Jen Wu
Article: Induction of Apoptosis by 11-Dehydrosinulariolide via Mitochondrial Dysregulation and ER Stress Pathways in Human Melanoma Cells
Mar. Drugs 2012, 10(8), 1883-1898; doi:10.3390/md10081883
http://www.mdpi.com/1660-3397/10/8/1883/
Aquapharm and c-LEcta collaboration on marine-derived biocatalysts
Posted On: July 25, 2012In a pioneering collaboration the leading Scottish biotechnology company Aquapharm and German industrial biotechnology firm c-LEcta are set to fast-track the discovery and commercialisation of a new wave of bio-catalysts.
c-LEcta is skilled in the identification and engineering of enzymes and strains for optimized bio-catalytic industry processes, whilst Aquapharm has proven expertise in harnessing the commercial potential of its unique collection of marine bacteria and fungi.
Together the partners will strengthen and expand their ability to provide innovative solutions across many market areas including production of natural, sustainably produced food, beverage and personal care ingredients.
Mar. Drugs, Volume 10, Issue 6 (June 2012), Pages Pages 1192-1421 Now Available
Posted On: June 26, 2012MDPI is pleased to announce the availability of the following:
Mar. Drugs, Volume 10, Issue 6 (June 2012), Pages Pages 1192-1421
http://www.mdpi.com/1660-3397/10/6/
Table of Contents:
Sheila Marie Pimentel-Elardo, Lubomir Grozdanov, Sebastian Proksch and Ute Hentschel
Article: Diversity of Nonribosomal Peptide Synthetase Genes in the Microbial Metagenomes of Marine Sponges
Mar. Drugs 2012, 10(6), 1192-1202; doi:10.3390/md10061192
http://www.mdpi.com/1660-3397/10/6/1192/
Shwu-Li Wu, Jui-Hsin Su, Chiung-Yao Huang, Chi-Jen Tai, Ping-Jyun Sung, Chih-Chung Liaw and Jyh-Horng Sheu
Article: Simplexins P–S, Eunicellin-Based Diterpenes from the Soft Coral Klyxum simplex
Mar. Drugs 2012, 10(6), 1203-1211; doi:10.3390/md10061203
http://www.mdpi.com/1660-3397/10/6/1203/
Sergey A. Dyshlovoy, Sergey N. Fedorov, Anatoly I. Kalinovsky, Larisa K. Shubina, Carsten Bokemeyer, Valentin A. Stonik and Friedemann Honecker
Article: Mycalamide A Shows Cytotoxic Properties and Prevents EGF-Induced Neoplastic Transformation through Inhibition of Nuclear Factors
Mar. Drugs 2012, 10(6), 1212-1224; doi:10.3390/md10061212
http://www.mdpi.com/1660-3397/10/6/1212/
Laura R. Hunt, Stephanie M. Smith, Kelsey R. Downum and Laura D. Mydlarz
Article: Microbial Regulation in Gorgonian Corals
Mar. Drugs 2012, 10(6), 1225-1243; doi:10.3390/md10061225
http://www.mdpi.com/1660-3397/10/6/1225/
Magbubah Essack, Vladimir B. Bajic and John A. C. Archer
Review: Conotoxins that Confer Therapeutic Possibilities
Mar. Drugs 2012, 10(6), 1244-1265; doi:10.3390/md10061244
http://www.mdpi.com/1660-3397/10/6/1244/
Shi-Ming Fang, Cheng-Bin Cui, Chang-Wei Li, Chang-Jing Wu, Zhi-Jun Zhang, Li Li, Xiao-Jun Huang and Wen-Cai Ye
Article: Purpurogemutantin and Purpurogemutantidin, New Drimenyl Cyclohexenone Derivatives Produced by a Mutant Obtained by Diethyl Sulfate Mutagenesis of a Marine-Derived Penicillium purpurogenum G59
Mar. Drugs 2012, 10(6), 1266-1287; doi:10.3390/md10061266
http://www.mdpi.com/1660-3397/10/6/1266/
Shang-Kwei Wang, Shyh-Yueh Puu and Chang-Yih Duh
Article: New 19-Oxygenated Steroids from the Soft Coral Nephthea chabrolii
Mar. Drugs 2012, 10(6), 1288-1296; doi:10.3390/md10061288
http://www.mdpi.com/1660-3397/10/6/1288/
Fuhang Song, Biao Ren, Ke Yu, Caixia Chen, Hui Guo, Na Yang, Hong Gao, Xueting Liu, Mei Liu, Yaojun Tong, Huanqin Dai, Hua Bai, Jidong Wang and Lixin Zhang
Article: Quinazolin-4-one Coupled with Pyrrolidin-2-iminium Alkaloids from Marine-Derived FungusPenicillium aurantiogriseum
Mar. Drugs 2012, 10(6), 1297-1306; doi:10.3390/md10061297
http://www.mdpi.com/1660-3397/10/6/1297/
Xi-Lin Lu, Zhong-Liang Xu, Xiao-Li Yao, Feng-Juan Su, Cheng-Hui Ye, Jing Li, Yong-Cheng Lin, Guang-Lei Wang, Jin-Sheng Zeng, Ru-Xun Huang, Jing-Song Ou, Hong-Shuo Sun, Li-Ping Wang, Ji-Yan Pang and Zhong Pei
Article: Marine Cyclotripeptide X-13 Promotes Angiogenesis in Zebrafish and Human Endothelial Cells via PI3K/Akt/eNOS Signaling Pathways
Mar. Drugs 2012, 10(6), 1307-1320; doi:10.3390/md10061307
http://www.mdpi.com/1660-3397/10/6/1307/
Jiun-Yang Chang, Chia-Ching Liaw, Ahmed Eid Fazary, Tsong-Long Hwang and Ya-Ching Shen
Article: New Briarane Diterpenoids from the Gorgonian Coral Junceella juncea
Mar. Drugs 2012, 10(6), 1321-1330; doi:10.3390/md10061321
http://www.mdpi.com/1660-3397/10/6/1321/
Haiyan Shi, Shanjiang Yu, Dong Liu, Leen van Ofwegen, Peter Proksch and Wenhan Lin
Article: Sinularones A–I, New Cyclopentenone and Butenolide Derivatives from a Marine Soft Coral Sinulariasp. and Their Antifouling Activity
Mar. Drugs 2012, 10(6), 1331-1344; doi:10.3390/md10061331
http://www.mdpi.com/1660-3397/10/6/1331/
Ying Zhao, Huan Chen, Zhuo Shang, Binghua Jiao, Bin Yuan, Weizhang Sun, Bingui Wang, Mingyong Miao and Caiguo Huang
Article: SD118-Xanthocillin X (1), a Novel Marine Agent Extracted from Penicillium commune, Induces Autophagy through the Inhibition of the MEK/ERK Pathway
Mar. Drugs 2012, 10(6), 1345-1359; doi:10.3390/md10061345
http://www.mdpi.com/1660-3397/10/6/1345/
Thierry Jauffrais, Jane Kilcoyne, Véronique Séchet, Christine Herrenknecht, Philippe Truquet, Fabienne Hervé, Jean Baptiste Bérard, Cíara Nulty, Sarah Taylor, Urban Tillmann, Christopher O. Miles and Philipp Hess
Article: Production and Isolation of Azaspiracid-1 and -2 from Azadinium spinosum Culture in Pilot Scale Photobioreactors
Mar. Drugs 2012, 10(6), 1360-1382; doi:10.3390/md10061360
http://www.mdpi.com/1660-3397/10/6/1360/
Roberta Teta, Gerardo Della Sala, Barbara Renga, Alfonso Mangoni, Stefano Fiorucci and Valeria Costantino
Article: Chalinulasterol, a Chlorinated Steroid Disulfate from the Caribbean Sponge Chalinula molitba. Evaluation of Its Role as PXR Receptor Modulator
Mar. Drugs 2012, 10(6), 1383-1390; doi:10.3390/md10061383
http://www.mdpi.com/1660-3397/10/6/1383/
Takashi Maoka, Harukuni Tokuda, Nobutaka Suzuki, Hideaki Kato and Hideo Etoh
Article: Anti-Oxidative, Anti-Tumor-Promoting, and Anti-Carcinogensis Activities of Nitroastaxanthin and Nitrolutein, the Reaction Products of Astaxanthin and Lutein with Peroxynitrite
Mar. Drugs 2012, 10(6), 1391-1399; doi:10.3390/md10061391
http://www.mdpi.com/1660-3397/10/6/1391/
Anette C. Elde, Ragnhild Pettersen, Per Bruheim, Johanna Järnegren and Geir Johnsen
Article: Pigmentation and Spectral Absorbance Signatures in Deep-Water Corals from the Trondheimsfjord, Norway
Mar. Drugs 2012, 10(6), 1400-1411; doi:10.3390/md10061400
http://www.mdpi.com/1660-3397/10/6/1400/
Banpeng Cao, Haixin Ding, Ruchun Yang, Xiaoji Wang and Qiang Xiao
Communication: Total Synthesis of a Marine Alkaloid—Rigidin E
Mar. Drugs 2012, 10(6), 1412-1421; doi:10.3390/md10061412
http://www.mdpi.com/1660-3397/10/6/1412/
ORNL Protein Analysis Investigates Marine Worm Community
Posted On: May 12, 2012Techniques used by researchers from the Department of Energy’s Oak Ridge National Laboratory to analyze a simple marine worm and its resident bacteria could accelerate efforts to understand more complex microbial communities such as those found in humans.
In a paper published in the Proceedings of the National Academy of Sciences, a multi-institutional research team analyzed the proteins found in a marine worm known as Olavius algarvensis. The worm lacks a digestive system and relies on microbes that live in its body to process its waste and provide energy. Previous research, however, had not untangled the metabolic details of this mutually beneficial, or symbiotic, relationship.
Growing International Interest In Oceanology To Benefit The Global Marine Biotechnology Market, According To New Report By Global Industry Analysts, Inc.
Posted On: April 24, 2012With growing environmental pollution throwing the spotlight on sustainable industrial development, there exists huge demand for suitable, scalable, economically, socially and environmentally sustainable feedstock options for the manufacturing industry. With sustainable feedstock production and delivery ballooning into a massive industry worldwide, the world’s oceans have emerged into the next frontier for investigative, biological resource development and management R&D projects.
For instance, marine-derived cosmetic ingredients, marine-derived molecules including enzymes, biopolymers and biomaterials, marine-derived pharmaceuticals, among others, are now becoming the mainstay of most R&D projects worldwide. The marine biotechnology sector is also attracting increased venture capital funds as is mirrored by the mushrooming of potential laden start-up firms focused on developing novel compounds from marine organisms.
As stated by the new market research report on Marine Biotechnology, Bioactive Substances represents one of the fastest growing market sectors trailing a projected CAGR of approximately 4.7% respectively.
The research report titled “Marine Biotechnology: A Global Strategic Business Report” announced by Global Industry Analysts Inc., provides a comprehensive review of the marine biotechnology markets, impact of recession on the markets, current market trends, key growth drivers, recent product introductions, recent industry activity, and profiles of major/niche global as well as regional market participants.
Marine Drugs Announces New Issue: Mar. Drugs, Volume 10, Issue 3
Posted On: March 23, 2012MDPI recently announced the publication of the following issue:
Mar. Drugs, Volume 10, Issue 3 (March 2012), Pages Pages 521-676
http://www.mdpi.com/1660-3397/10/3/
Table of Contents:
Jing Tong, Hank Trapido-Rosenthal, Jun Wang, Youwei Wang, Qing X. Li and Yuanan Lu
Article: Antiviral Activities and Putative Identification of Compounds in Microbial Extracts from the Hawaiian Coastal Waters
Mar. Drugs 2012, 10(3), 521-538; doi:10.3390/md10030521
http://www.mdpi.com/1660-3397/10/3/521/
Li Sun, Dongli Li, Meihua Tao, Yuchan Chen, Feijun Dan and Weimin Zhang
Article: Scopararanes C–G: New Oxygenated Pimarane Diterpenes from the Marine Sediment-Derived Fungus Eutypella scoparia FS26
Mar. Drugs 2012, 10(3), 539-550; doi:10.3390/md10030539
http://www.mdpi.com/1660-3397/10/3/539/
Zeping Xie, Bing Liu, Hongpeng Wang, Shengxiang Yang, Hongyu Zhang, Yipeng Wang, Naiyun Ji, Song Qin and Hartmut Laatsch
Article: Kiamycin, a Unique Cytotoxic Angucyclinone Derivative from a Marine Streptomyces sp.
Mar. Drugs 2012, 10(3), 551-558; doi:10.3390/md10030551
http://www.mdpi.com/1660-3397/10/3/551/
Yun-Jing Chai, Cheng-Bin Cui, Chang-Wei Li, Chang-Jing Wu, Cong-Kui Tian and Wei Hua
Article: Activation of the Dormant Secondary Metabolite Production by Introducing Gentamicin-Resistance in a Marine-Derived Penicillium purpurogenum G59
Mar. Drugs 2012, 10(3), 559-582; doi:10.3390/md10030559
http://www.mdpi.com/1660-3397/10/3/559/
Danielle F. Mello, Eliza S. de Oliveira, Renato C. Vieira, Erik Simoes, Rafael Trevisan, Alcir Luiz Dafre and Margherita Anna Barracco
Article: Cellular and Transcriptional Responses of Crassostrea gigas Hemocytes Exposed in Vitro to Brevetoxin (PbTx-2)
Mar. Drugs 2012, 10(3), 583-597; doi:10.3390/md10030583
http://www.mdpi.com/1660-3397/10/3/583/
Yan-Bo Zeng, Hui Wang, Wen-Jian Zuo, Bo Zheng, Tao Yang, Hao-Fu Dai and Wen-Li Mei
Article: A Fatty Acid Glycoside from a Marine-Derived Fungus Isolated from Mangrove PlantScyphiphora hydrophyllacea
Mar. Drugs 2012, 10(3), 598-603; doi:10.3390/md10030598
http://www.mdpi.com/1660-3397/10/3/598/
Nicolantonio D’Orazio, Eugenio Gemello, Maria Gammone, Massimo de Girolamo, Cristiana Ficoneri and Graziano Riccioni
Review: Fucoxantin: A Treasure from the Sea
Mar. Drugs 2012, 10(3), 604-616; doi:10.3390/md10030604
http://www.mdpi.com/1660-3397/10/3/604/
Wan-Yu Lin, Yi Lu, Bo-Wei Chen, Chiung-Yao Huang, Jui-Hsin Su, Zhi-Hong Wen, Chang-Feng Dai, Yao-Haur Kuo and Jyh-Horng Sheu
Article: Sarcocrassocolides M–O, Bioactive Cembranoids from the Dongsha Atoll Soft CoralSarcophyton crassocaule
Mar. Drugs 2012, 10(3), 617-626; doi:10.3390/md10030617
http://www.mdpi.com/1660-3397/10/3/617/
Hou-Jin Li, Ying-Lu Xie, Zhong-Liang Xie, Ying Chen, Chi-Keung Lam and Wen-Jian Lan
Article: Chondrosterins A–E, Triquinane-Type Sesquiterpenoids from Soft Coral-Associated FungusChondrostereum sp.
Mar. Drugs 2012, 10(3), 627-638; doi:10.3390/md10030627
http://www.mdpi.com/1660-3397/10/3/627/
Min-Juan Xu, Xiao-Jin Liu, Yi-Lei Zhao, Dong Liu, Zhen-Hao Xu, Xiao-Meng Lang, Ping Ao, Wen-Han Lin, Song-Lin Yang, Zhi-Gang Zhang and Jun Xu
Article: Identification and Characterization of an Anti-Fibrotic Benzopyran Compound Isolated from Mangrove-Derived Streptomyces xiamenensis
Mar. Drugs 2012, 10(3), 639-654; doi:10.3390/md10030639
http://www.mdpi.com/1660-3397/10/3/639/
Yuta Kudo, Takeshi Yasumoto, Keiichi Konoki, Yuko Cho and Mari Yotsu-Yamashita
Article: Isolation and Structural Determination of the First 8-epi-type Tetrodotoxin Analogs from the Newt, Cynops ensicauda popei, and Comparison of Tetrodotoxin Analogs Profiles of This Newt and the Puffer Fish, Fugu poecilonotus
Mar. Drugs 2012, 10(3), 655-667; doi:10.3390/md10030655
http://www.mdpi.com/1660-3397/10/3/655/
Zhuang Han, Ying Xu, Oliver McConnell, Lingli Liu, Yongxin Li, Shuhua Qi, Xiangzhong Huang and Peiyuan Qian
Article: Two Antimycin A Analogues from Marine-Derived Actinomycete Streptomyces lusitanus
Mar. Drugs 2012, 10(3), 668-676; doi:10.3390/md10030668
http://www.mdpi.com/1660-3397/10/3/668/
Scots and Aussie scientists team up to research marine microbes
Posted On: March 12, 2012A leading Scottish marine biotechnology firm has joined forces with the Australian Institute of Marine Science (AIMS) in a bid to discover innovative and high-value products from micro-organisms.
Scientists from Aquapharm Biotechnology are to be given exclusive commercial access to a selection of Australian marine microbes in the AIMS Bioresources Library.
Aquapharm believes the deal will lead to the discovery of useful new active ingredients for use in pharmaceutical, nutritional and personal care products.
Jon Williams, VP Commercial at Aquapharm, explained: “AIMS is amongst the world’s top specialist research institutions, and it has cultivated a sizeable collection of marine micro-organisms from Australia’s unique marine territory. This territory spans an immense 16 million square kilometres, leading to high biodiversity and the potential for novel microbes and their products.
“Aquapharm has signed an agreement with AIMS that grants us exclusive commercial access to a select range of these organisms for testing and development, with the option to conclude an exclusive licence agreement for commercialization if they are found to be suitable.
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